B6db families : 5_1_1

	Activities \| Families \| Sequences \| Fold types \| References \| Help

5.1.1.17

Activity

5.1.1.17

Description

Isopenicillin N epimerase

Notes

A small family of bacterial enzymes. Distantly related sequences also occur in plants, and are sometimes annotated as isopenicillin N epimerase.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

CAA39986 (Lysobacter lactamgenus); CEFD_NOCLA (Nocardia lactamdurans); ZP_02732865 (Gemmata obscuriglobus); CEFD_STRCL (Streptomyces clavuligerus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

CEFD_NOCLA

Domain interval

20-389

Catalytic site

219 K

References

Kimura, H.; Izawa, M.; Sumino, Y. (1996) Molecular analysis of the gene cluster involved in cephalosporin biosynthesis from Lysobacter lactamgenus YK90 Appl Microbiol Biotechnol 44 589-96.

Coque, J. J.; Martin, J. F.; Liras, P. (1993) Characterization and expression in Streptomyces lividans of cefD and cefE genes from Nocardia lactamdurans: the organization of the cephamycin gene cluster differs from that in Streptomyces clavuligerus Mol Gen Genet 236 453-8.

Articles on 5.1.1.17

last changed

2009/07/03 14:44