B6db families : beta

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beta transaminase

Activity

Description

Beta-amino acid--oxoglutarate aminotransferase (2.6.1.-)

Notes

A small subgroup of bacterial sequences. Even though they catalyze a reaction similar to that of EC 2.6.1.19 (GABA transaminase) they are only distantly related to the bacterial enzymes in family 2.6.1.19b.

The most closely related family is glutamate semialdehyde 2,1-aminomutase (5.4.3.8).

PDB

4AO4;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

YP_548313 (Polaromonas sp. JS666); YP_002944294 (Variovorax paradoxus S110); YP_001862264 (Burkholderia phymatum); ABL74379 (Mesorhizobium sp. LUK);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

ABL74379

Domain interval

65-378

Catalytic site

280 K

References

Kim J, Kyung D, Yun H, Cho BK, Seo JH, Cha M, Kim BG (2007) Cloning and characterization of a novel beta-transaminase from Mesorhizobium sp. strain LUK: a new biocatalyst for the synthesis of enantiomerically pure beta-amino acids Appl Environ Microbiol 73 1772-82.

Articles on beta.transaminase

last changed

2019/03/04 13:05