B6db families : cap15

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cap15

Activity

Description

(5'S,6'R)-GlyU monooxygenase-decarboxylase (1.14.99.-)

Notes

Small family of enzymes from actinobacteria, most similar to D-glucosaminate-6-phosphate ammonia-lyases (family 4.3.1.29).

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_084175183 (Actinokineospora spheciospongiae); WP_093809035 (Streptomyces sp. Ncost-T6T-1); AKC92635 (Amycolatopsis sp. SANK 60206); BAJ19050 (Streptomyces sp. SANK 62799);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

BAJ19050

Domain interval

36-387

Catalytic site

230 K

References

Huang Y, Liu X, Cui Z, Wiegmann D, Niro G, Ducho C, Song Y, Yang Z, Van Lanen SG. (2018) Pyridoxal-5'-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, alfa-amino acid monooxygenase-decarboxylase. Proc Natl Acad Sci U S A. 115 974-979.

Articles on cap15

last changed

2018/02/27 13:14