B6db families : cuab

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cuab

Activity

Description

Curvulamine intermediate synthase (2.3.1.-)

Notes

A small family of fungal enzymes.
Their reaction is somewhat similar to that of fum8 enzymes, but sequences are related only distantly. Instead, proteins in this family most closely resemble 8-amino-7-oxononanoate synthases (family 2.3.1.47).

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Fungi

XP_014072737 (Bipolaris maydis ATCC 48331); XP_007711337 (Bipolaris zeicola 26-R-13); QHD56301 (Curvularia sp. IFB-Z10); XP_007700279 (Bipolaris sorokiniana ND90Pr); XP_007689407 (Bipolaris oryzae ATCC 44560);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

QHD56301

Domain interval

61-440

Catalytic site

277 K

References

Dai GZ, Han WB, Mei YN, Xu K, Jiao RH, Ge HM, Tan RX (2020) Pyridoxal-5'-phosphate-dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi Proc Natl Acad Sci U S A. 117 1174-1180.

Articles on cuab

last changed

2020/02/17 09:50