B6db families : glii

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glii

Activity

glii

Description

Twin carbon-sulfur lyase (4.4.1.-)

Notes

Tiny family, based on the only validated sequence from A. fumigatus.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Fungi

XP_001258081 (Aspergillus fischeri NRRL 181); GAQ03190 (Aspergillus lentulus); KEY77194 (Aspergillus fumigatus var. RP-2014); AAW03309 (Aspergillus fumigatus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAW03309

Domain interval

51-440

Catalytic site

266 K

References

Scharf DH, Chankhamjon P, Scherlach K, Heinekamp T, Roth M, Brakhage AA, Hertweck C. (2012) Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway. Angew Chem Int Ed Engl 51 10064-8.

Articles on glii

last changed

2016/10/03 11:59