B6db families : gm853

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gm853

Activity

Description

Leucine decarboxylase (4.1.1.-)

Notes

Family built around three functionally validated enzyme from mouse.
These are Fold-type III sequences, very closely related to those in family 4.1.17_1 (ornithine decarboxylases) and odcp (ornithine decarboxylase antizyme inhibitor).

PLP Fold Type

III

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type III

Number of sequences

Sequences in seed alignment

Metazoa

XP_002720724 (Oryctolagus cuniculus); XP_020018672 (Castor canadensis); XP_232777 (Rattus norvegicus); XP_019694617 (Felis catus); XP_006158213 (Tupaia chinensis); XP_008693048 (Ursus maritimus); ERE85399 (Cricetulus griseus); XP_006503261 (Mus musculus); XP_020951430 (Sus scrofa); XP_019585704 (Rhinolophus sinicus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

XP_006503261

Domain interval

52-385

Catalytic site

81 K

References

Lambertos A, Ramos-Molina B, Cerezo D, López-Contreras AJ, Peñafiel R (2018) The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase Biochim Biophys Acta 1862 365-376.

Articles on gm853

last changed

2019/02/13 13:28