B6db families : mm260

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mm260

Activity

Description

L-threonine kinase (decarboxylating) (2.7.1.-)

Notes

Family built around the characterized enzyme from Methanosarcina mazei Go1.
The proteins are most similar to bacterial phosphothreonine decarboxylases (family 4.1.1.81); the most obvious difference is an extra C-terminal extension of unknown function, which contains a putative metal-binding motif.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Archaea

WP_011500103 (Methanococcoides burtonii); WP_011033992 (Methanosarcina mazei); WP_048167182 (Methanosarcina thermophila); WP_091689489 (Methanococcoides vulcani); WP_013898683 (Methanosalsum zhilinae); WP_013036759 (Methanohalophilus mahii); WP_011308365 (Methanosarcina barkeri); WP_048127507 (Methanosarcina lacustris); WP_091933783 (Methanolobus profundi); AKB84339 (Methanococcoides methylutens MM1); WP_094229183 (Methanolobus psychrotolerans);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

WP_011033992

Domain interval

37-378

Catalytic site

234 K

References

Tavares NK, Zayas CL, Escalante-Semerena JC (2018) The Methanosarcina mazei MM2060 Gene Encodes a Bifunctional Kinase/Decarboxylase Enzyme Involved in Cobamide Biosynthesis Biochemistry 57 4478-4495.

Articles on mm260

last changed

2018/07/25 14:33