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B6db families: mur24
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mur24
Activity mur24
Description Disaccharide alkyl acceptor aminobutyryltransferase (4.1.1.-)
Notes A family of very divergent (an also, sequence-wise, very diverse) bacterial enzymes, remotely similar to ACC synthases (4.4.1.14_a) that also employ AdoMet as a substrate.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm		Fold type I
Number of sequences 5
Sequences in seed alignment
BacteriaBAO20191 (Sphaerisporangium sp. SANK 60911); ACQ63621 (Streptomyces sp. MK730-62F2); BAJ05886 (Streptomyces sp. SANK 60405); ADZ45336 (Streptomyces sp. NRRL 30471); WP_086789548 (Crossiella equi);

DISPLAY: Fasta format, alignment, hmm, hmm_local
Reference sequence ADZ45336
Domain interval 40-337
Catalytic site 234 K
 
References
 Cui Z, Overbay J, Wang X, Liu X, Zhang Y, Bhardwaj M, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG (2020) Pyridoxal-5'-phosphate-dependent Alkyl Transfer in Nucleoside Antibiotic Biosynthesis Nat Chem Biol in press.

Articles on mur24
last changed 2020/06/16 10:26

B6db families