B6db families : pumg

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pumg

Activity

Description

Pseudouridine-5'-aldehyde aminotransferase (2.6.1.-)

Notes

A family of enzymes based on the validated sequence from Streptomyces sp. ID38640.
They are most closely related to family lipo (which catalyzes a very similar reaction) and to other families FTI omega-aminotransferases such as 2.6.1.18 (beta-alanine-pyruvate transaminase).

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_031191256 (Streptomyces sp. NRRL B-11253); AVT42376 (Streptomyces sp. ID38640); ARZ66675 (Streptomyces albireticuli); WP_016471192 (Streptomyces albus DSM 40763);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AVT42376

Domain interval

36-437

Catalytic site

289 K

References

Sosio M, Gaspari E, Iorio M, Pessina S, Medema MH, Bernasconi A, Simone M, Maffioli SI, Ebright RH, Donadio S (2018) Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics Cell Chem Biol 25 540-549.

Articles on pumg

last changed

2018/04/04 17:11