B6db families : tuzn1299

	Activities \| Families \| Sequences \| Fold types \| References \| Help

tuzn1299

Activity

Description

Branched chain amino acid--pyruvate transaminase (low-specificity) (2.6.1.-)

Notes

Family composed only of archaeal enzymes. The most similar sequences in the database are found in family 2.6.1.42a (classic branched-chain amino acid aminotransferase).

PDB

5CE8;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type IV

Number of sequences

Sequences in seed alignment

Archaea

ABO09173 (Pyrobaculum calidifontis JCM 11548); KUO83260 (Pyrobaculum sp. JCHS_4); WP_013680111 (Thermoproteus uzoniensis); WP_069807611 (Vulcanisaeta thermophila); WP_014126068 (Thermoproteus tenax); WP_013604112 (Vulcanisaeta moutnovskia); KJR73586 (Thermoproteus sp. AZ2); AAL64820 (Pyrobaculum aerophilum str. IM2); AET32742 (Pyrobaculum ferrireducens); WP_081226729 (Thermoproteus sp. CP80);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

WP_013680111

Domain interval

29-258

Catalytic site

150 K

References

Stekhanova TN, Rakitin AL, Mardanov AV, Bezsudnova EY, Popov VO (2017) A Novel highly thermostable branched-chain amino acid aminotransferase from the crenarchaeon Vulcanisaeta moutnovskia Enzyme Microb Technol 96 127-134.

Bezsudnova EY, Stekhanova TN, Suplatov DA, Mardanov AV (2016) Experimental and computational studies on the unusual substrate specificity of branched-chain amino acid aminotransferase from Thermoproteus uzoniensis Arch. Biochem. Biophys. 607 27-36.

Boyko KM, Stekhanova TN, Nikolaeva AY, Mardanov AV, Rakitin AL, Ravin NV, Bezsudnova EY, Popov VO (2016) First structure of archaeal branched-chain amino acid aminotransferase from Thermoproteus uzoniensis specific for L-amino acids and R-amines Extremophiles 20 215-25.

Articles on tuzn1299

last changed

2017/12/22 08:27