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dsad |
Description |
L-Isoleucine-3-epimerase (5.1.1.-) |
Alternative names |
DsaD (gene name);
MfnO (gene name); |
Catalyzed reaction |
L-isoleucine = L-allo-isoleucine |
Cofactor |
Pyridoxal-phosphate, DsaE protein |
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DsaD from the desotamide biosynthetic pathway in Streptomyces scopuliridis, and MfnO from the marformycin biosynthetic pathway in Streptomyces drozdowiczii drive l-allo-Ile generation in each respective system.
Epimerase activity is conferred to these enzymes by a separate, small protein (termed DsaE in S. scopuliridis MfnH in S. drozdowiczii) which belongs to the NTF2_like superfamily and may be considered, in a sense, a cofactor for DsaD. |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) dsad
BRENDA (activities) dsad
KEGG (pathways) dsad
PLPMDB (PLP mutants) dsad
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References |
Articles on dsad |
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last changed |
2018/04/11 13:13 |
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