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B6db activities: ind4

Description Arginine 2,4-dioxidase (1.3.3.-)
Catalyzed reaction L-Arginine + 2O(2) = 2,3,4,5 tetradehydroarginine + 2H(2)O(2)
Cofactor Pyridoxal phosphate
Comments ??? The enzyme in vitro catalyzes other reactions involving miolecular oxygen, including the oxidative deamination of L-Arg.
The enzyme, from Streptomyces griseus, is involved in indolmycin biosynthesis.
Organisms -Eubacteria


ind4 (0)
Links Enzyme (activities) ind4
BRENDA (activities) ind4
KEGG (pathways) ind4
PLPMDB (PLP mutants) ind4
 Du YL, Singh R, Alkhalaf LM, Kuatsjah E, He HY, Eltis LD, Ryan KS (2016) A pyridoxal phosphate-dependent enzyme that oxidizes an unactivated carbon-carbon bond Nat Chem Biol 12 194-9.

 Du YL, Alkhalaf LM, Ryan KS (2015) In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly Proc Natl Acad Sci U S A 112 2717-22.

Articles on ind4
last changed 2019/06/20 13:08

B6db activities