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B6db families: 4.2.1.22

4.2.1.22
Activity 4.2.1.22
Description Cystathionine beta-synthase.
Notes Mammalian cystathionine beta-synthases, but not the yeast enzyme, also bind a heme molecule.
Additional_domain CBS_HUMAN 1-400
PDB 1JBQ;1M54;
PLP Fold Type II
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type II

Number of sequences
23
Sequences in seed alignment
BacteriaNP_215593 (Mycobacterium tuberculosis); CAE81156 (Bdellovibrio bacteriovorus); AAS03341 (Mycobacterium avium); AAG48621 (Streptomyces venezuelae); CAB89449.1 (Streptomyces coelicolor A3(2)); AAN24961 (Bifidobacterium longum); BAB96806.1 (Rhodococcus erythropolis); ZP_00059346 (Thermobifida fusca);
FungiAF422799_1 (Magnaporthe grisea); EAK93698 (Candida albicans); CBS_YEAST (Saccharomyces cerevisiae); AAL09565 (Pichia pastoris); EAA78329 (Gibberella zeae); EAA30070 (Neurospora crassa);
MetazoaAAD13393 (Takifugu rubripes); AAF50862 (Drosophila melanogaster); CBS_RAT (Rattus norvegicus); CBS_HUMAN (Homo sapiens); AAH44091 (Xenopus laevis);
Other_EukaryaCBS_DICDI (Dictyostelium discoideum); AAK16397 (Trypanosoma cruzi); AAN31486 (Phytophthora infestans); AAF71541 (Leishmania tarentolae);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence CBS_HUMAN
Domain interval 80-376
Catalytic site 119 K
 
References Articles on 4.2.1.22
last changed 2008/03/27 19:12

B6db families