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B6db families:
Description Serine racemase
Notes Validated eukaryotic enzymes (from metazoa and plants) are similar in sequence to serine ammonia-lyases (, and in fact they often catalyze dehydration of serine to pyruvate in addition to serine racemization.

In bacteria amino acid racemization is usually carried out by fold-type III enzymes (that we have grouped in the family).
One bacterial enzyme with a sequence similar to those herein and showing some serine racemase activity (WP_013961474 from Roseobacter litoralis; see Kubota et al. 2016, Microbiology 162 53-61) is probably acting physiologically as an erythro-3-hydroxy-D-aspartate ammonia-lyase (family bhcb), as suggested by the genomic context.

PLP Fold Type II
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type II

Number of sequences 0
Reference sequence SRR_HUMAN
Domain interval 19-314
Catalytic site 56 K
References Articles on
last changed 2019/11/20 17:14

B6db families