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B6db families: 2.6.1.1.a

2.6.1.1 a
Activity 2.6.1.1
Description Aspartate aminotransferase (family a)
Notes This aspartate aminotransferase subfamily includes functionally characterized enzymes from eukariotes.
PDB 7AAT;1YAA;3MEB;3HLM;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Reference sequence AATC_YEAST
Domain interval 30-405
Catalytic site 255 K
 
References
 Abendroth J, Choi R, Wall A, Clifton MC, Lukacs CM, Staker BL, Van Voorhis W, Myler P, Lorimer DD, Edwards TE (2015) Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia Acta Crystallogr F Struct Biol Commun 71 566-71.

 Nadeem, M.S.; Rashid, N; Iqbal, M.; Gardner, Q.A.; Akhtar, M. (2011) First cloning and characterization of aspartate aminotransferase from river buffalo (Bubalus bubalis) Biologia 66 1202-1210.

 Donini S, Ferrari M, Fedeli C, Faini M, Lamberto I, Marletta AS, Mellini L, Panini M, Percudani R, Pollegioni L, Caldinelli L, Petrucco S, Peracchi A. (2009) Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism Biochem J 422 265-72.

 Vernal, J.; Cazzulo, J.; Nowicki, C. (2003) Cloning and heterologous expression of a broad specificity aminotransferase of Leishmania mexicana promastigotes1 FEMS Microbiol Lett 229 217-22.

 Gebhardt, J.S.; Wadsworth, G.J.; Matthews, B.F. (1998) Characterization of a single soybean cDNA encoding cytosolic and glyoxysomal isozymes of aspartate aminotransferase Plant Mol Biol 37 99-108.

 Jeffery, C. J.; Barry, T.; Doonan, S.; Petsko, G. A.; Ringe, D. (1998) Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase Protein Sci 7 1380-7.

 Reynolds, P. H.; Smith, L. A.; Dickson, J. M.; Jones, W. T.; Jones, S. D.; Rodber, K. A.; Carne, A.; Liddane, C. P. (1992) Molecular cloning of a cDNA encoding aspartate aminotransferase-P2 from lupin root nodules Plant Mol Biol 19 465-72.

 Udvardi, M. K.; Kahn, M. L. (1991) Isolation and analysis of a cDNA clone that encodes an alfalfa (Medicago sativa) aspartate aminotransferase Mol Gen Genet 231 97-105.

 Mattes, U.; Jaussi, R.; Ziak, M.; Juretic, N.; Lindenmann, J. M.; Christen, P. (1989) Structure of cDNA of cytosolic aspartate aminotransferase of chicken and its expression in E. coli Biochimie 71 411-6.

 Nagashima, F.; Tanase, S.; Fukumoto, Y.; Joh, T.; Nomiyama, H.; Tsuzuki, T.; Shimada, K.; Kuramitsu, S.; Kagamiyama, H.; Morino, Y. (1989) cDNA cloning and expression of pig cytosolic aspartate aminotransferase in Escherichia coli: amino-terminal heterogeneity of expressed products and lack of its correlation with enzyme function Biochemistry 28 1153-60.

 Horio, Y.; Tanaka, T.; Taketoshi, M.; Nagashima, F.; Tanase, S.; Morino, Y.; Wada, H. (1988) Rat cytosolic aspartate aminotransferase: molecular cloning of cDNA and expression in Escherichia coli J Biochem (Tokyo) 103 797-804.

 Martini, F.; Angelaccio, S.; Barra, D.; Pascarella, S.; Maras, B.; Doonan, S.; Bossa, F. (1985) The primary structure of mitochondrial aspartate aminotransferase from human heart Biochim Biophys Acta 832 46-51.

 Barra, D.; Bossa, F.; Doonan, S.; Fahmy, H. M.; Hughes, G. J.; Martini, F.; Petruzzelli, R.; Wittmann-Liebold, B. (1980) The cytosolic and mitochondrial aspartate aminotransferases from pig heart. A comparison of their primary structures, predicted secondary structures and some physical properties Eur J Biochem 108 405-14.

Articles on 2.6.1.1.a
last changed 2018/10/15 13:18

B6db families