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B6db families: 4.2.1.22

4.2.1.22
Activity 4.2.1.22
Description Cystathionine beta-synthase
Notes Mammalian cystathionine beta-synthases, but not the yeast enzyme, also bind a heme molecule.
Additional_domain CBS_HUMAN 1-400
PDB 1JBQ;1M54;4L0D;5OHX;
PLP Fold Type II
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type II

Number of sequences
24
Sequences in seed alignment
BacteriaZP_00059346 (Thermobifida fusca); CAB89449 (Streptomyces coelicolor A3(2)); AAS03341 (Mycobacterium avium); BAB96806 (Rhodococcus erythropolis); NP_215593 (Mycobacterium tuberculosis); AAG48621 (Streptomyces venezuelae); CAE81156 (Bdellovibrio bacteriovorus); AAN24961 (Bifidobacterium longum);
FungiEAA78329 (Gibberella zeae); AF422799 (Magnaporthe grisea); EAA30070 (Neurospora crassa); EAK93698 (Candida albicans); CBS_YEAST (Saccharomyces cerevisiae); AAL09565 (Pichia pastoris);
MetazoaCBS_HUMAN (Homo sapiens); AAD13393 (Takifugu rubripes); AAF50862 (Drosophila melanogaster); AAH44091 (Xenopus laevis); CBS_RAT (Rattus norvegicus); NP_001035353 (Apis mellifera);
Other_EukaryaAAN31486 (Phytophthora infestans); AAF71541 (Leishmania tarentolae); AAK16397 (Trypanosoma cruzi); CBS_DICDI (Dictyostelium discoideum);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence CBS_HUMAN
Domain interval 80-376
Catalytic site 119 K
 
References Articles on 4.2.1.22
last changed 2018/03/06 13:28

B6db families