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B6db Fold_types: 2

Fold type II

Two domains comprised of mixed alpha/beta structure with PLP bound between these two domains.

Prototype sequence:
TRPB_SALTY - Tryptophan synthase

Prototype structure:
PDB 1BKS;

PLP-dependent families with this fold:

2.3.1.263 (14) 2.5.1.113 (10) 2.5.1.134 (13) 2.5.1.140 (10) 2.5.1.144 (5) 2.5.1.47 (51) 2.5.1.65 (5) 2.5.1.76 (10) 2.6.99.3 (14) 2.8.5.1 (5) 3.5.99.7 (16) 4.2.1.122 (29) 4.2.1.20 (57) 4.2.1.22 (24) 4.2.3.1 (52) 4.3.1.15 (7) 4.3.1.16 (13) 4.3.1.17_a (26) 4.3.1.17_b (10) 4.3.1.18_a (14) 4.3.1.19 (39) 4.4.1.15 (14) 4.4.1.25 (7) 4.4.1.28_b (7) 4.4.1.28_d (12) 4.4.1.9_a (11) 4.4.1.9_b (12) 5.1.1.13_a (5) 5.1.1.13_b (3) 5.1.1.14 (4) 5.1.1.18 (19) abmd (6) bhcb (11) cys_hydrolase (9) l-phenylserine_dehydratase (6) njxa (8) uncharacterized_family_1a1d (3)

 Steiner EM, Böth D, Lössl P, Vilaplana F, Schnell R, Schneider G. (2014) CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase. J Bacteriol 196 3410-20.

 Hyde, C. C.; Ahmed, S. A.; Padlan, E. A.; Miles, E. W.; Davies, D. R. (1988) Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium J Biol Chem 263 17857-71.


B6db Fold_types