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B6db Fold_types: 2

Fold type II

Two domains comprised of mixed alpha/beta structure with PLP bound between these two domains.

Prototype sequence:
TRPB_SALTY - Tryptophan synthase

Prototype structure:

PLP-dependent families with this fold:

 Steiner EM, Böth D, Lössl P, Vilaplana F, Schnell R, Schneider G. (2014) CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase. J Bacteriol 196 3410-20.

 Hyde, C. C.; Ahmed, S. A.; Padlan, E. A.; Miles, E. W.; Davies, D. R. (1988) Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium J Biol Chem 263 17857-71.

B6db Fold_types